Peripheral Blood Mononuclear Cell (PBMC) Inducible Nitric Oxide Synthase (iNOS) Expression and Activity as a Potential Tumor Marker in Hepatocellular Carcinoma (HCC)
نویسنده
چکیده
Clinical Pathology and Medical Oncology* Department, NCI, Cairo University, Medical Research Centre, Ain-Shams University** and Molecular Cardiac Unit, Duke University, USA, *** Director of Cardiac metabolism, laboratory research division, research drive, research park 4 room 01, Duke University, Medical Centre, Urham, NC 27710 USA. Journal of the Egyptian Nat. Cancer Inst., Vol. 14, No. 2, June: 145-151, 2002
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The effect of 17β-estradiol on gene expression of calcitonin gene-related peptide and some pro-inflammatory mediators in peripheral blood mononuclear cells from patients with pure menstrual migraine
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Inducible nitric oxide synthase (iNOS) gene expresses a calcium calmudolin-independent enzyme which can catalyse NO production from L-arginine. The induction of iNOS activity has been demonstrated in a wide variety of cell types under stimulation with cytokines and lipopoly saccharide (LPS). Previous studies indicated that all nitric oxide synthases (NOS) activated in human umbilical vein endot...
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